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Putting mice into hibernation causes a major loss of synapses

Researchers at OIST induced a hibernation-like state in mice, erasing over half their synapses, yet the mice retained their memories. This challenges the prevailing hypothesis that memories are physically stored in synaptic connections, suggesting memory encoding may be more robust than previously thought.

Background

Memory storage in the brain has long been theorized to depend on synaptic strengthening and physical changes in neural connections. This study provides unexpected evidence that memories can survive dramatic synaptic restructuring.

Source
Ars Technica
Published
Aug 22, 2026 at 07:22 PM
Score
7.0 / 10